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Neuro & Sleep
Preclinical evidence only

Semax + Selank blend

A supplier blend of Semax and Selank, two Russian-developed peptides, in one vial.

Regulatory status: Not a medicine outside Russia. The combination has not been studied.

Default vial

20 mg

Default mix

3 mL

Reported range

Varies with the blend ratio

Draw (U-100)

7.5 u

Intranasal
Every day
4w on / 2w off

Two Russian-developed peptides in one vial, each with its own entry. Combining them has not been studied; the research that exists is on each one separately.

Where these numbers come from

Community convention

No human dosing trial defines a dose for this compound. The numbers here are the values community calculators pre-fill — reference only. The published work studies Semax and Selank separately; the combination has not been studied.

Reviewed October 2026

What it is

  • Two peptides in a single vial, each with its own Pep-Tidy entry.
  • Semax is an ACTH fragment analogue; Selank is derived from tuftsin. They were developed separately for different purposes.
  • Both are registered medicines in Russia and neither is approved in the US or EU.
  • Usually sold for intranasal use.

How it is described to act

  1. 1

    Given together intranasally or by injection, depending on the preparation.

  2. 2

    Each behaves as it does alone.

  3. 3

    The rationale offered is pairing a cognitive peptide with an anxiolytic one; nothing published tests the pairing.

  4. 4

    No outcome has been measured for the combination.

What the research has looked at

What the research covers

  • The published work studies Semax and Selank separately, mostly in Russian journals. See their individual entries.
  • No published study tests them together.

Strength of evidence: Preclinical evidence only

No study tests this combination. The individual compounds have research concentrated in one country's literature.

What is published comes from cell and animal studies. Findings in those models frequently do not carry over to people.

Reported cautions and unknowns

  • A blend is several compounds at once, so an adverse effect cannot be traced to any one of them. Running components separately first is the only way to know which does what.
  • Ratios are set by the supplier, not by any standard, so two vials with the same name can contain quite different amounts.
  • The safety of the combination has not been studied. What is known, where anything is known, applies to each compound on its own.
  • There are no combined pharmacokinetic or toxicity data for any of these blends, so interaction risk is unquantified.
  • The FDA's 2026 compounding-committee briefing on BPC-157 documented adverse-event reports and gaps in impurity characterisation for that single peptide.
  • Sterility, identity and concentration of multi-peptide compounded vials vary by supplier; only a current third-party Certificate of Analysis can confirm what a vial actually contains.

References

There are none. A search of the published literature returns no studies of this compound — no human trials, no animal work, no cell studies. Anything claimed about it elsewhere is not drawn from published research on this molecule.

Handling this vial

  • Lyophilized vials are generally stored at 2–8 °C and kept out of light; once reconstituted with bacteriostatic water they are refrigerated and commonly discarded after 28 days.
  • Mix by aiming water down the vial wall and rolling gently — do not shake — and never re-freeze a reconstituted vial.
  • Pep-Tidy cannot verify what is in your vial. Ask your supplier for a current Certificate of Analysis (HPLC/MS).

Semax + Selank blend questions people ask

How do you reconstitute Semax + Selank blend?

A common starting point for a 20 mg vial of Semax + Selank blend is 3 mL of bacteriostatic water, which gives 6.67 mg per mL. Aim the water down the inside wall of the vial, let it dissolve on its own, and roll gently instead of shaking. Pep-Tidy's reconstitution calculator will recalculate the numbers for any other vial size or water volume you use.

How many units of Semax + Selank blend is one dose?

At 6.67 mg per mL, that works out to about 7.5 units on a U-100 insulin syringe for a 500 mcg dose. Change the vial size, water volume, or target dose in the calculator and the syringe reading updates with it. This is arithmetic, not a dosing recommendation.

What dosing schedule is reported for Semax + Selank blend?

Published and community sources describe Varies with the blend ratio, intranasal, every day, typically run 4 weeks on and 2 weeks off. These figures describe what has been reported, not what anyone should take — talk to a licensed clinician first.

How should Semax + Selank blend be stored?

Lyophilized Semax + Selank blend vials are generally kept at 2–8 °C and out of light. Once reconstituted with bacteriostatic water they are refrigerated and commonly discarded after about 28 days. Never re-freeze a reconstituted vial and never shake it.

Read this before you act on anything above

Everything on this page is a summary of what other people have published — it is not medical advice, not a recommendation, and not a dosing instruction. Reported dose ranges describe what appears in the literature or in community protocols, not what anyone should take. Talk to a licensed clinician before using any peptide.

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